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Biosciences and Biotechnology
Harnessing a natural geochemical reaction to combat antibiotic resistance
Antibiotics have allowed for the widespread control of bacterial infections, which had been the leading cause of death historically. However, the overuse of traditional antibiotics in humans and animals resulted in the emergence of stronger, more potent bacterial strains that are no longer treatable with conventional antibiotics. Researchers at Lawrence Livermore National…
Lab researchers and collaborators to develop new vaccine against three biothreat pathogens
Scientists from Lawrence Livermore National Laboratory (LLNL) and three other institutions are seeking to develop a multi-pathogen vaccine that will protect against three bacterial biothreat pathogens. Led by LLNL, the team includes disease experts from the University of New Mexico Health Sciences Center (UNMHSC), the University of Nevada, Reno School of Medicine (UNR Med)…
Unprecedented multiscale model of protein behavior linked to cancer-causing mutations
Lawrence Livermore National Laboratory (LLNL) researchers and a multi-institutional team of scientists have developed a highly detailed, machine learning-backed multiscale model revealing the importance of lipids to the signaling dynamics of RAS, a family of proteins whose mutations are linked to numerous cancers. Published by the Proceedings of the National Academy of…
In the neighborhood of microalgae, location is key to bacterial carbon use
Microscopic algae are responsible for half of the global atmospheric carbon fixed from the atmosphere through photosynthesis, and may be used as a sustainable bioenergy source. The water immediately outside their cells, called the “phycosphere,” is rich with algal-excreted organic carbon, and is an ideal ecosystem for bacterial growth. However, detecting and measuring…
PLS postdocs battle it out at the 2021 Research Slam!
Lawrence Livermore National Laboratory’s (LLNL’s) fifth annual Research Slam! took place virtually on October 6th and featured 14 LLNL postdocs, 9 of which represented the Physical and Life Sciences Directorate (PLS). Over 300 people logged on to attend the live two-hour event, enthusiastically cheering for their favorite postdocs in the comment section. Each finalist was…
Cancer therapies and nuclear material detection get a boost from newly discovered protein
Lawrence Livermore National Laboratory (LLNL) and Penn State scientists have demonstrated how a protein can be recovered and purified for radioactive metals like actinium that could be beneficial for both next-generation drugs used in cancer therapies and the detection of nuclear activities. Radioactive metals hold unique and essential places in a variety of medical…
Lawrence Livermore Research Slam! winners advance to Bay Area competition
The top winners of the recent Lawrence Livermore National Laboratory (LLNL) Research Slam!, a speaking competition for postdocs, will advance to the Bay Area Research SLAM set for Thursday, Oct. 28. The Bay Area Research SLAM! is a collaboration between the Bay Area’s national labs (Lawrence Berkeley National Laboratory, LLNL, Sandia National Laboratories and SLAC National…
Lawrence Livermore develops promising antidote for nerve agent exposure
Scientists at Lawrence Livermore National Laboratory (LLNL) have developed a new, versatile antidote to counteract exposure to nerve agent poisoning. The work, appearing in the journal Scientific Reports, was the result of a highly iterative process built in collaboration between LLNL’s Global Security Directorate, its Forensic Science Center and the U.S. Army Medical…
Researchers discover the first nerve-agent antidote that crosses the blood–brain barrier
A team led by LLNL scientists has discovered the first antidote against nerve-agent poisoning that crosses the blood–brain barrier (BBB). Their research, published in Scientific Reports, comes on the heels of a recent resurgence of nerve agents in transnational conflicts. Organophosphorus-based nerve agents (OPNAs)—including sarin, soman, and VX—cross the BBB and are…
Predicting Combat Wound Recovery
Recent advances in body armor and other battlefield damage control strategies have increased the proportion of survivable blast-related combat injuries. Over the last few decades, treatment of warfighters surviving increasingly severe injuries has created new challenges across the Department of Defense’s Military Health System.
Tackling the COVID-19 Pandemic
Long before the COVID-19 pandemic gripped the globe, Lawrence Livermore National Laboratory had been preparing to help the nation contend with biological threats. From its inception, Livermore has focused its scientific and technological expertise on strengthening the security of the United States.
It’s only natural: Using environmental microbes to remove uranium from groundwater
Uranium contamination of soils and groundwater in the United States represents a significant health risk and will require multiple remediation approaches. Remediation strategies for uranium-contaminated sites have been the focus of research for decades due to the former production of nuclear materials across the United States. The U.S. Environmental Protection Agency (EPA)…
Lab offers forum on machine learning for industry
Lawrence Livermore National Laboratory (LLNL) is looking for participants and attendees from industry, research institutions and academia for the first-ever Machine Learning for Industry Forum (ML4I), a three-day virtual event starting Aug. 10. Pre-registrations are open for the forum, which aims to foster and illustrate the adoption of machine learning methods for…
COVID-19 HPC Consortium reflects on past year
COVID-19 HPC Consortium scientists and stakeholders met virtually on March 23 to mark the consortium’s one-year anniversary, discussing the progress of research projects and the need to pursue a broader organization to mobilize supercomputing access for future crises. The White House announced the launch of the public-private consortium, which provides COVID-19 researchers…
3D-printable gas diffusion layers promise improved performance in electrochemical reduction of CO2
Using carbon dioxide (CO2) emissions to create value-added products is an attractive approach to reduce net greenhouse gas emissions. Processes such as the electrochemical reduction of CO2 to ethylene and ethanol offer a pathway to producing commodity chemicals without fossil fuels when they are powered using low-carbon electricity. Gas diffusion electrode (GDE) assemblies…
Fighting Bacterial Infections with Machine Learning
Scientists in the Forensic Science Center at Lawrence Livermore have partnered with San Diego State University and UCSD to advance bacteriophage therapy.
Physics of particle dispersion may lend insight into reducing the airborne spread of COVID-19 virus
Lawrence Livermore National Laboratory (LLNL) scientists are leveraging their extensive experience studying the movement of airborne hazards to better understand the movement of virus-like particles through the air and to identify effective countermeasures. DNATrax released in a conference room.While the burden of airborne diseases is known to be large, its true scope is…
LLNL weapon engineers, biologists deliver critical samples to identify skin proteins left on IEDs
Following a terrorist bombing, can the bomb maker be identified by skin proteins left on the bomb components they handled? To address this question, Lawrence Livermore National Laboratory (LLNL) personnel from Weapons Complex Integration (WCI) and Global Security (GS) Forensic Science and Biosecurity Centers (FSC/BSC) subjected notional bomb components handled by LLNL…
Lawrence Livermore’s popular lecture series goes virtual to cover COVID-19
Lawrence Livermore National Laboratory's (LLNL) popular lecture series, "Science on Saturday," is going virtual in 2021 with the theme “Combating COVID-19.” The series, targeted to middle and high school students, runs Saturdays at 10 a.m. Feb. 6 through Feb. 27. Each Saturday will feature a different lecture presented by leading Lawrence Livermore National Laboratory…
LLNL and United Kingdom company to collaborate on development of universal coronavirus vaccine
ConserV Bioscience Limited (CBL) and Lawrence Livermore National Laboratory (LLNL) have agreed to collaborate on the development of a broad-spectrum or “universal” coronavirus vaccine. This collaboration brings together CBL’s expertise in identifying antigens and LLNL’s nanolipoprotein delivery system. The vaccine has been designed to provide broad-spectrum protection…