Lawrence Livermore National Laboratory

Amy Rasley

Biomedical Scientist - Host-Pathogen Biology Group
Biosciences and Biotechnology Division

 +1 925-423-1284

Ph.D. Immunology
University of North Carolina at Charlotte
B.S. Zoology
Weber State University

Research Interests

Dr. Rasley is a biomedical scientist working in the host-pathogen biology group within the Biosciences and Biotechnology Division.  Her past research efforts during her Ph.D. and Postdoctoral tenures focused on understanding the initiation of innate immune responses within the central nervous system during bacterial infections.  Current research interests include understanding the initiation of innate immune responses to bacterial pathogens and host-pathogen interactions.  Ongoing studies involve characterization of the host response to Francisella tularensis and Yersinia pestis infection using DNA microarray technology and imaging approaches as well as identifying bacterial genes important for pathogenesis and disease progression.

Selected Publications

Loots, G., P. S. G. Chain, S. Mabery, A. Rasley, E. Garcia, and I. Ovcharenko, " Array2BIO: A Comprehensive Suite of Utilities for the Analysis of Microarray Data," BMC Bioinformatics 7: 307-315 (2006).

Rasley, A., S. L. Tranguch, D. M. Rati, and I. Marriott, "Murine glia express the immunosuppressive cytokine, interleukin-10, following exposure to Borrelia burgdorferi or Neisseria meningitidis," Glia53(6): 583-592 (2006).

Rasley, A., I. Marriott, K. L. Bost, J. Anguita, "Substance P augments B. burgdorferi induced PGE2 production by murine microglia," Journal of Immunology  172: 5707-5713 (2004).

Rasley, A., K. L. Bost, and I. Marriott, "Murine gammaherpesvirus-68 elicits high levels of IL-12p40, but not IL-12p70, production by murine microglia,"  Journal of Neurovirology 10: 171-180 (2004).

Bowman, C. C., A. Rasley, S. L.Tranguch, and I. Marriott, "Cultured astrocytes express Toll-like receptors for bacterial products," Glia 43: 281-291 (2003).

Taylor, W. R., A. Rasley, K. L. Bost, and I. Marriott, "Murine gammaherpesvirus-68 infected microglia and astrocytes produce proinflammatory cytokines,"  Journal of Neuroimmunology 136: 75-83 (2003).

Rasley, A., I. Marriott, and J. Anguita, "Borrelia burgdorferi induces inflammatory mediator production by murine microglia," Journal of Neuroimmunology 130: 22-31 (2002).

Rasley, A., K. L. Bost, J. K. Olson, S. D. Miller, and I. Marriott, "Expression of Functional NK-1 Receptors in Murine Microglia," Glia 37: 258-267 (2002).

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