Lawrence Livermore National Laboratory

Sahar El-Etr

Research Staff
Biosciences and Biotechnology Division

 +1 925-423-0383

Ph.D. Bacterial Pathogenesis
University of Nebraska Medical Center
M.S. Microbiology
University of Hawaii
B.Sc. Biochemistry and Zoology
Makerere University, Kampala, Uganda

Research Interests

Bacterial pathogenesis and host pathogen interactions. Currently investigating the interactions of Francisella tularensis with amoebae and their role in the environmental persistence of F. tularensis and their impact on pathogenesis. Also studying the response of mammalian host cells to F. tularensis infection.

Honors and Awards

Awarded an LDRD-LW grant in 2008 from LLNL/ DOE to investigate the role of dendritic cells in the pathogenesis of tularemia.

Selected Publications

S. H. El-Etr, J. J. Margolis, D. Monack, R. A. Robison, M. Cohen, E. Moore and A. Rasley. "Prolonged survival of Francisella tularensis type A strains in Acanthamoeba castellanii: implications for environmental survival and virulence". Submitted to Infect. Immun. (2008)

Mehta, P. K., A. K. Pandey, S. Subbian, S. H. El-Etr, S. L. Cirillo, M. M. Samrakandi, J. D. Cirillo. "Identification of Mycobacterium marinum macrophage infection mutants." Microb. Path. 40, 139 (2006).

El-Etr, S. H., A. Mueller, L. S. Tompkins, S. Falkow and D. S. Merrell. "Phosphorylation-independent effects of CagA during interaction between Helicobacter pylori and T84 polarized monolayers." J. Infect. Dis. 190, 1516 (2004).

El-Etr, S. H., S. Subbian, S. L. Cirillo and J. D. Cirillo. "Identification of two Mycobacterium marinum loci that affect interactions with macrophages." Infect. Immun. 72, 6902 (2004).

El-Etr, S. H., L. Yan and J. D. Cirillo. "Fish monocytes as a model for mycobacterial host-pathogen Interactions." Infect. Immun. 69, 7310 (2001).

El-Etr, S. H., and J. D. Cirillo. "Entry mechanisms of mycobacteria." Front. Biosci. 6, 737 (2001). Invited Review.

Cirillo, S. L. G, L. E. Bermudez, S. H. El-Etr, G. E. Duhamel and J. D. Cirillo. "The Legionella pneumophila gene rtxA is involved in virulence." Infect. Immun. 69, 508 (2001).

Peruski, L. F., B. A. Kay, R. A. El-Yazeed, S. H. El-Etr, A. Cravioto, T. F. Wierzba, M. Rao, N. El-Ghorab, H. Shaheen, S. F. Khalil, K. Kamal, M. O. Wasfy, A.-M Svennerholm, J. D. Clemens and S. Savarino. "Phenotypic diversity of enterotoxigenic Escherichia coli (ETEC) isolated from community-based study of pediatric diarrhea in rural Egypt." J. Clin. Microbiol. 37, 2974 (1999).

Oyofo, B. A., Z. S. Mohran, T. F. Ismail, S. H. El-Etr, L. F. Peruski Jr., A. M. Churilla, and M. Gabriel. "Enteropathogens associated with diarrhea in military personnel during Operation Bright Star 96." J. Mil. Medicine 162, 396 (1997).

Oyofo, B. A., Z. S. Mohran, S. H. El-Etr, M. O. Wasfy and L. F. Peruski. "Detection of enterotoxigenic Escherichia coli, Shigella and Campylobacter spp by multiplex PCR assay." J. Diarr. Dis. Res. 14, 207 (1996).

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